PDP1= Pyruvat-Dehydrogenase-Phosphatase- Deficiency (exercise intolerance and post-exercised collapse)
EIC= Exercise Induced Collapse (muscle weakness, lack of coordination and life-threatening collapse after intense exercise)

PRA=Die progressive Retinaatrophie (cells deteriorate over time, eventually leading to blindness)

These diseases are inherited in an autosomal recessive manner, i.e. dogs only can get sick if both...... the maternal and paternal
PDP1 / EIC / PRA gene have this genetic mutation.

It means, these diseases can be easily excluded by selecting the right pairing..

There are 3 results of a test, e.g.:
Genotyp N/N = frei /clear/normal
Genotyp N/E = Träger / carrier (Genträger - dog itself will never get sick with this disease)
Genotpy E/E = erkrankt/affected

When breeding, it is therefore important to ensure that either clear x clear, clear x carrier (or clear x affected) is mated.
This ensures that no puppy can get sick with these diseases..

It is therefore very important for the breeder to know the genotypes, through laboratory tests or derived from inheritance. Therefore, the laboratory test results are registered with the breeding clubs and passed on with an entry in the pedigree or - as shown below - when registering with a certificate, so the status is also known for "export dogs"..


    

You would like to inform you about the health test results of the ancestors of the puppy of your choice? ... ..and you should, too!

If the ancestors are from abroad, you possibly may find it in the databases of the Kennelclubs.

All you need is the full name of the dog, kennel name or studbook number. And with just a few clicks, you can also get access to the results of the health tests of its parents, siblings and their offspring. Very helpful to get an idea about the health status in the line, about diseases that are more common ..... about a possible family disposition for certain diseases and of course also IF? and WHICH? Tests were ever made. Because not in all breeding clubs all breed specific health tests are also obligatory .... resp. there are exceptions to this duty.

Here you can find the databases:

KC - (Kennel Club United Kingdom)
Database - all breeds: https://www.thekennelclub.org.uk/services/public/mateselect/test/Default.aspx
   
SKK - (Schwedischer Kennel Klub)

Database - all breeds:

http://www.rasdata.nu

Clumber Spaniel -
Search with Kennelname:
http://www.rasdata.nu/clumber/htmlhund/htmlhund.htm
   

AKC - (Amerikanischer Kennel Club)

Database - all breeds: https://www.ofa.org/advanced-search?search=advanced
   

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